SULFHYDRYL GROUPS AND THE INTERACTION BETWEEN THE HEMES IN HEMOGLOBIN
نویسندگان
چکیده
منابع مشابه
Sulfhydryl Groups and the Interaction between the Hemes in Hemoglobin
1. Dialysis of a hemoglobin solution against slightly alkaline buffer (pH 8.68) causes a decrease in heme-heme interaction. The value of n in Hill's equation drops from 2.9 to 2.0, while the oxygen affinity increases slightly. Addition of glutathione largely reverses the effects of dialysis (n rises from 2.0 to 2.5 to 2.6). 2. Addition of the sulfhydryl reagent, p-chloromercuribenzoate (1.8 x 1...
متن کاملThe possibility of direct interaction between the hemes in hemoglobin.
The Problem.-Heme-heme interaction in hemoglobin may be defined briefly as the dependence of the ligand-binding properties of a particular subunit heme upon the state of liganding of other subunit hemes in the same tetramer. The existence of such dependence is clearly demonstrated by a comparison of the equilibrium ligand-binding properties of the isolated a and , subunits with that of hemoglob...
متن کاملthe relationship between learners critical thinking ability and their performance in the reading sections of the tofel and ielts test
the study reflected in this thesis aims at finding out relationships between critical thinking (ct), and the reading sections of tofel and ielts tests. the study tries to find any relationships between the ct ability of students and their performance on reading tests of tofel and academic ielts. however, no research has ever been conducted to investigate the relationship between ct and the read...
15 صفحه اولInteraction between tetraethylthiuram disulfide and the sulfhydryl groups of D-amino acid oxidase and of hemoglobin.
Inhibition of the crystallized hog kidney flavoenzyme, D-amino acid oxidase, by tetraethylthiuram disulfide (disulCram, TETD) has been found to involve the sulfhydryldisulfide exchange reaction; primary products of the interaction between oxidase and reagent are diethyldithiocarbamate ion and a derived protein carrying mixed disulfide linkages, each of which consists of an enzyme thiol sulfur a...
متن کاملSulfhydryl Groups and the Structure of Hemoglobin
1. Addition of 2 moles of mersalyl, mercuric chloride, p-chloromercuribenzoate (PCMB), or methyl mercury hydroxide per mole of hemoglobin greatly reduces heme-heme interactions (n), yet these substances have quite different effects on the oxygen affinity (-log p(50)). Mersalyl and mercuric chloride at this concentration each increase the oxygen affinity, while PCMB and methyl mercury have littl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1952
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.36.1.1